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Home / Primary Antibodies / Promotion

OGG1 antibody

SKU : BHA10805972

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Mfr.No.	FNab05980
Alternative Names	MMH ; MUTM ; OGH1
Background	This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alteative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alteative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alteative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Categories	Primary Antibodies
Clonality	polyclonal
Description	DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion.
Host	Rabbit
Immunogen	8-oxoguanine DNA glycosylase
Isotype	IgG
Molecular Weight	36 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	MMH, MUTM, OGH1

Uniprot	O15527
Gene Id	4968
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab05980.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805972	FNab05980	100ug	$300		Add to Cart

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