This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
Clonality
polyclonal
Host
Rabbit
Immunogen
Niemann-Pick disease, type C2
Immunogen Region
Niemann-Pick disease, type C2
Isotype
IgG
Molecular Weight
20 kDa
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Synonyms
HE1, Niemann Pick disease, type C2, NPC2
Uniprot
P61916
Gene Id
10577
Research Area
Cardiovascular, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:500
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10049.pdf" target="_blank">Data Sheet</ a>