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Home / Primary Antibodies / Polyclonal Antibodies

NCS1 antibody

SKU : BHA10805587

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Mfr.No.	FNab05595
Alternative Names	FLUP ; FREQ
Background	This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N- type voltage-gated calcium channel (By similarity).
Host	Rabbit
Immunogen	frequenin homolog (Drosophila)
Isotype	IgG
Molecular Weight	20 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	FLUP, FREQ

Uniprot	P62166
Gene Id	23413
Research Area	Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab05595.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805587	FNab05595	100ug	$300		Add to Cart

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