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Home / Primary Antibodies / Promotion

MMP2 antibody

SKU : BHA10810635

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Mfr.No.	FNab10848
Background	This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alteative splicing results in multiple transcript variants encoding different isoforms.
Clonality	polyclonal
Host	Rabbit
Immunogen	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
Immunogen Region	transducin-like enhancer of split 1
Isotype	IgG
Molecular Weight	72 kDa
Reactivity	Human, Mouse
Synonyms	72 kDa gelatinase, 72 kDa type IV collagenase, CLG4, CLG4A, Gelatinase A, Matrix metalloproteinase 2, MMP 2, MMP II, MMP2, MONA, TBE 1

Uniprot	P08253
Gene Id	4313
Research Area	Metabolism, Cancer, Cardiovascular

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10855.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810635	FNab10848	100ug	$300		Add to Cart

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