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Home / Primary Antibodies / Promotion

MCL1 antibody

SKU : BHA10805044

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Mfr.No.	FNab05052
Alternative Names	BCL2L3
Background	This gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alteative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alteatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Host	Rabbit
Immunogen	myeloid cell leukemia sequence 1 (BCL2-related)
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	BCL2L3

Uniprot	Q07820
Gene Id	4170
Research Area	Developmental biology, Stem Cells, Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Manual	FNab05052.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10805044	FNab05052	100ug	$300		Add to Cart

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