This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alteatively spliced variants encoding distinct isoforms have been described.
Categories
Primary Antibodies
Clonality
polyclonal
Description
The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Host
Rabbit
Immunogen
microtubule-associated protein 2
Isotype
IgG
Molecular Weight
70-85 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DKFZp686I2148, MAP 2, MAP2, MAP2A, MAP2B, MAP2C
Uniprot
P11137
Gene Id
4133
Research Area
Stem Cells, Immunology, Cancer, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)