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Home / Primary Antibodies / Polyclonal Antibodies

LILRB4 antibody

SKU : BHA10810470

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Mfr.No.	FNab10516
Background	This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	Leukocyte immunoglobulin-like receptor subfamily B member 4
Immunogen Region	Leukocyte immunoglobulin-like receptor subfamily B member 4
Isotype	IgG
Molecular Weight	49 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Synonyms	LILRB4, CD85K, ILT-3, ILT3, LIR-5, LIR5

Uniprot	Q8NHJ6

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10516.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810470	FNab10516	100ug	$300		Add to Cart

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