Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface(plasma membrane), and inter-and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome, adhesion when expressed on the cell surface (plasma membrane), and inter- and intracellular signal transduction. Protects cells from the toxic effects of methylating mutagens.
Host
Rabbit
Immunogen
lysosomal-associated membrane protein 2
Isotype
IgG
Molecular Weight
110-130kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
membrane
Synonyms
CD107b, LAMP 2, LAMP2, LAMPB, LGP110
Uniprot
P13473
Gene Id
3920
Research Area
Immunology, Cardiovascular, Metabolism
Weight
45kDa,observed 55kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)