This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alteate splicing results in multiple transcript variants of this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin.
Host
Rabbit
Immunogen
kinectin 1 (kinesin receptor)
Isotype
IgG
Molecular Weight
166 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
CG1, KIAA0004
Uniprot
Q86UP2
Gene Id
3895
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)