May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D (By similarity).
Clonality
polyclonal
Host
Rabbit
Immunogen
klotho
Immunogen Region
klotho
Isotype
IgG
Molecular Weight
62,120 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
KL, klotho
Uniprot
Q9UEF7
Gene Id
9365
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10869.pdf" target="_blank">Data Sheet</ a>