Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Host
Rabbit
Immunogen
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
Isotype
IgG
Molecular Weight
50-82 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
hSK3, K3, KCa2.3, KCNN3, SK3, SKCa 3, SKCA3
Uniprot
Q9UGI6
Gene Id
3782
Research Area
Developmental biology, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)