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Home / Primary Antibodies / Promotion

IRS1 antibody

SKU : BHA10804392

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Mfr.No.	FNab04400
Background	This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
Categories	Primary Antibodies
Clonality	polyclonal
Description	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Host	Rabbit
Immunogen	insulin receptor substrate 1
Isotype	IgG
Molecular Weight	180 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	HIRS 1, insulin receptor substrate 1, IRS 1, IRS1

Uniprot	P35568
Gene Id	3667
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP, IF
Description	ELISA ; WB ; IHC ; IP ; IF
Tested Application	WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Manual	FNab04400.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804392	FNab04400	100ug	$300		Add to Cart

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