The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Supports IL-2 independent and IL-4 independent growth of helper T-cells.
Host
Rabbit
Immunogen
interleukin 9
Isotype
IgG
Molecular Weight
19 kDa
Reactivity
Human, Rat
Regulatory
RUO
Synonyms
Cytokine P40, HP40, IL 9, IL9, interleukin 9, P40, T cell growth factor P40
Uniprot
P15248
Gene Id
3578
Research Area
Immunology, Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)