The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
interleukin 1, alpha
Isotype
IgG
Molecular Weight
35kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
IL-1A, IL1, IL1-ALPHA, IL1F1
Uniprot
P01583
Gene Id
3552
Research Area
Stem Cells, Immunology, Cardiovascular, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)