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Home / Primary Antibodies / Polyclonal Antibodies

IGF2BP2 antibody

SKU : BHA10804166

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Mfr.No.	FNab04172
Alternative Names	IMP2 ; VICKZ2
Background	This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alteative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes.
Categories	Primary Antibodies
Clonality	polyclonal
Description	RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta- actin/ACTB and MYC transcripts.
Host	Rabbit
Immunogen	insulin-like growth factor 2 mRNA binding protein 2
Isotype	IgG
Molecular Weight	66 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	IMP2, VICKZ2

Uniprot	Q9Y6M1
Gene Id	10644
Research Area	Epigenetics

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:200 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab04172.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804166	FNab04172	100ug	$300		Add to Cart

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