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Home / Primary Antibodies / Promotion

IGF1R antibody

SKU : BHA10804164

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Mfr.No.	FNab04170
Background	IGF1R, also named as CD221, is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). IGF1R binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity, the activated IGF1R is involved in cell growth and survival control. It is crucial for tumor transformation and survival of malignant cell. IGF1R is a heterotetrameric receptor, composed of two alpha subunits (130 kDa each) and two beta subunits (~98 kDa each) (PMID: 6279656). Both the alpha and beta subunits are synthesized from a single mRNA precursor. The precursor is then glycosylated, proteolytically cleaved, and crosslinked by cysteine bonds.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	insulin-like growth factor 1 receptor
Isotype	IgG
Molecular Weight	70 kDa,90-100 kDa, 130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD221, IGFIR, IGFR, JTK13

Uniprot	P08069
Gene Id	3480
Research Area	Developmental biology, Signal Transduction, Metabolism, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IP
Description	ELISA ; WB ; IP
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab04170.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804164	FNab04170	100ug	$300		Add to Cart

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