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Home / Primary Antibodies / Polyclonal Antibodies

ID3 antibody

SKU : BHA10804109

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Mfr.No.	FNab04115
Alternative Names	1R21 ; BHLHB25 ; HEIR1
Background	The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.
Host	Rabbit
Immunogen	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Isotype	IgG
Molecular Weight	62 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	1R21, BHLHB25, HEIR1

Uniprot	Q02535
Gene Id	3399
Research Area	Developmental biology, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Manual	FNab04115.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804109	FNab04115	100ug	$300		Add to Cart

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