HTT(huntingtin), also named as HD and IT15, belongs to the huntingtin family. HTT may play a role in microtubule-mediated transport or vesicle function. Defects in HTT are the cause of Huntington disease (HD) which is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.
Clonality
polyclonal
Host
Rabbit
Immunogen
Huntingtin
Immunogen Region
Huntingtin
Isotype
IgG
Molecular Weight
348 kDa
Reactivity
Human, Mouse
Recommended Dilution
IHC: 1:50-1:500; IF: 1:50-1:500
Synonyms
HD, HD protein, HTT, Huntingtin, Huntington disease protein, IT15
Uniprot
P42858
Gene Id
3064
Research Area
Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)