Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones(H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Clonality
polyclonal
Host
Rabbit
Immunogen
histone deacetylase 10
Immunogen Region
histone deacetylase 10
Isotype
IgG
Molecular Weight
68 kDa
Reactivity
Human
Recommended Dilution
IHC: 1:20-1:200
Synonyms
HD10, HDAC10, histone deacetylase 10
Uniprot
Q969S8
Gene Id
83933
Research Area
Epigenetics, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10065.pdf" target="_blank">Data Sheet</ a>