The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores(PubMed:27281216). The physiological relevance of this observation is unknown(Probable).
Clonality
polyclonal
Host
Rabbit
Immunogen
gasdermin B
Immunogen Region
gasdermin B
Isotype
IgG
Molecular Weight
47 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000
Synonyms
GSDMB, GSDML, PP4052, PRO2521, gasdermin-B
Uniprot
Q8TAX9
Gene Id
55876
Research Area
Cell Division and Proliferation
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10147.pdf" target="_blank">Data Sheet</ a>