GRP75(also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA(HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson s disease.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
heat shock 70kDa protein 9(mortalin)
Isotype
IgG
Molecular Weight
74 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CSA, GRP 75, GRP75, Heat shock 70 kDa protein 9, HSPA9, HSPA9B, Mortalin, MOT, mot 2, MOT2, MTHSP75, PBP74, Peptide binding protein 74
Uniprot
P38646
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)