GLUT2 is a member of glucose transporters or GLUTs which catalyze the glucose transport across plasma membrane. GLUT2 is selectively expressed in hepatocytes, pancreatic beta cells, and absorptive renal and intestinal epithelial cells. GLUT2 is required to maintain normal glucose homeostasis and normal function and development of the endocrine pancreas. Its absence leads to symptoms characteristic of non-insulin-dependent diabetes mellitus. GLUT2 has 60-70 kDa fully glycosylated matured form and a nonglycosylated form around 38-45 kDa.
Clonality
polyclonal
Host
Rabbit
Immunogen
solute carrier family 2,facilitated glucose transporter member 2
Immunogen Region
solute carrier family 2,facilitated glucose transporter member 2
Isotype
IgG
Molecular Weight
57 kDa
Reactivity
Human, Rat, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Synonyms
GLUT 2, GLUT2, SLC2A2
Uniprot
P11168
Gene Id
6514
Research Area
Stem Cells, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09867.pdf" target="_blank">Data Sheet</ a>