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Home / Primary Antibodies / Polyclonal Antibodies

GLRX antibody

SKU : BHA10803484

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Mfr.No.	FNab03490
Alternative Names	GRX
Background	This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alteatively spliced transcript variants encoding the same protein have been identified.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Host	Rabbit
Immunogen	glutaredoxin (thioltransferase)
Isotype	IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	GRX

Uniprot	P35754
Gene Id	2745
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF
Description	ELISA ; WB ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab03490.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803484	FNab03490	100ug	$300		Add to Cart

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