The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alteatively spliced variants, encoding the same protein, have been identified.
Categories
Primary Antibodies
Clonality
polyclonal
Description
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Host
Rabbit
Immunogen
FK506 binding protein 2, 13kDa
Isotype
IgG
Molecular Weight
14 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
FKBP13
Uniprot
P26885
Gene Id
2286
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)