This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alteately spliced transcript variants which encode different protein isoforms have been described.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May have an involvement in muscle development or hypertrophy.
Host
Rabbit
Immunogen
four and a half LIM domains 1
Isotype
IgG
Molecular Weight
40 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
SLIM1
Uniprot
Q13642
Gene Id
2273
Research Area
Developmental biology, Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)