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Home / Primary Antibodies / Promotion

FANCL antibody

SKU : BHA10803004

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Mfr.No.	FNab03010
Alternative Names	PHF9
Background	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alteative splicing results in two transcript variants encoding different isoforms.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.
Host	Rabbit
Immunogen	Fanconi anemia, complementation group L
Isotype	IgG
Molecular Weight	38 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	PHF9

Uniprot	Q9NW38
Gene Id	55120
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:200 - 1:2000; IHC: 1:20 - 1:200

Manual	FNab03010.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803004	FNab03010	100ug	$300		Add to Cart

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