Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone(CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.
Clonality
polyclonal
Host
Rabbit
Immunogen
ELKS/RAB6-interacting/CAST family member 1
Immunogen Region
ELKS/RAB6-interacting/CAST family member 1
Isotype
IgG
Molecular Weight
130 kDa,110 kDa, 82 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
ELKS, KIAA1081, RAB6IP2, ERC1
Uniprot
Q8IUD2
Gene Id
23085
Research Area
Developmental biology, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10262.pdf" target="_blank">Data Sheet</ a>