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Home / Primary Antibodies / Polyclonal Antibodies

EIF2S3 antibody

SKU : BHA10802695

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Mfr.No.	FNab02701
Alternative Names	EIF2G
Background	The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit.
Categories	Primary Antibodies
Clonality	polyclonal
Description	As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a teary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).
Host	Rabbit
Immunogen	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Isotype	IgG
Molecular Weight	45 kDa
Reactivity	Human, Rat
Regulatory	RUO
Synonyms	EIF2G

Uniprot	P41091
Gene Id	1968
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab02701.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802695	FNab02701	100ug	$300		Add to Cart

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