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Home / Primary Antibodies / Polyclonal Antibodies

DDR1 antibody

SKU : BHA10810039

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Mfr.No.	FNab10051
Background	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Clonality	polyclonal
Host	Rabbit
Immunogen	discoidin domain receptor tyrosine kinase 1
Immunogen Region	discoidin domain receptor tyrosine kinase 1
Isotype	IgG
Molecular Weight	101 kDa
Reactivity	Human, Rat
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:500
Synonyms	CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

Uniprot	Q08345
Gene Id	780
Research Area	Immunology, Cardiovascular, Metabolism, Signal Transduction

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10051.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810039	FNab10051	100ug	$300		Add to Cart

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