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Home / Primary Antibodies / Polyclonal Antibodies

CYP46A1 antibody

SKU : BHA10802161

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Mfr.No.	FNab02167
Alternative Names	CYP46
Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be retued to the liver for catabolism.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Involved in the tuover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. Has also activity with xenobiotic compounds, such as clotrimazole.
Host	Rabbit
Immunogen	cytochrome P450, family 46, subfamily A, polypeptide 1
Isotype	IgG
Molecular Weight	57 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CYP46

Uniprot	Q9Y6A2
Gene Id	10858
Research Area	Developmental biology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab02167.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10802161	FNab02167	100ug	$300		Add to Cart

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