Receptor for the CX3C chemokine fractalkine(CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions(PubMed:9390561, PubMed:23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein(in vitro)(PubMed:9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1(PubMed:14607932).
Clonality
polyclonal
Host
Rabbit
Immunogen
chemokine(C-X3-C motif) receptor 1
Immunogen Region
chemokine(C-X3-C motif) receptor 1
Isotype
IgG
Molecular Weight
50 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Synonyms
CMKBRL1, GPR13
Uniprot
P49238
Gene Id
1524
Research Area
Stem Cells, Immunology, Signal Transduction, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10034.pdf" target="_blank">Data Sheet</ a>