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Home / Primary Antibodies / Promotion

COTL1 antibody

SKU : BHA10801882

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Mfr.No.	FNab01888
Alternative Names	CLP
Background	This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
Host	Rabbit
Immunogen	coactosin-like 1
Isotype	IgG
Molecular Weight	14 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CLP

Uniprot	Q14019
Gene Id	23406
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Manual	FNab01888.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801882	FNab01888	100ug	$300		Add to Cart

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