This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the intealization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
Clonality
polyclonal
Host
Rabbit
Immunogen
MRC2
Immunogen Region
MRC2
Isotype
IgG
Molecular Weight
190 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500 - 1:2000
Synonyms
CD280, CLEC13E, ENDO180, UPARAP, MRC2
Uniprot
Q9UBG0
Gene Id
9902
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10304.pdf" target="_blank">Data Sheet</ a>