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Home / Primary Antibodies / Polyclonal Antibodies

BLMH antibody

SKU : BHA10800902

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Mfr.No.	FNab00907
Background	Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.
Categories	Primary Antibodies
Clonality	polyclonal
Description	The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B- aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
Host	Rabbit
Immunogen	bleomycin hydrolase
Isotype	IgG
Molecular Weight	50 kDa
Reactivity	Human, Rat
Regulatory	RUO

Uniprot	Q13867
Gene Id	642
Research Area	Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50

Manual	FNab00907.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800902	FNab00907	100ug	$300		Add to Cart

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