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Home / Primary Antibodies / Promotion

ARNT2 antibody

SKU : BHA10800590

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Mfr.No.	FNab00595
Alternative Names	BHLHE1 ; KIAA0307
Background	This gene encodes a member of the basic-helix-loop-helix-Per-At-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function (PubMed:24022475). Specifically recognizes the xenobiotic response element (XRE).
Host	Rabbit
Immunogen	aryl-hydrocarbon receptor nuclear translocator 2
Isotype	IgG
Molecular Weight	79 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BHLHE1, KIAA0307

Uniprot	Q9HBZ2
Gene Id	9915
Research Area	Signal Transduction, Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00595.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800590	FNab00595	100ug	$300		Add to Cart

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