ARHGAPs, such as ARHGAP25, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 (PubMed 15254788)).
Categories
Primary Antibodies
Clonality
polyclonal
Description
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Host
Rabbit
Immunogen
Rho GTPase activating protein 25
Isotype
IgG
Molecular Weight
70 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
KIAA0053
Uniprot
P42331
Gene Id
9938
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)