May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus caveosum smooth muscle, the clitoral corpus caveosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus caveosum smooth muscle, the clitoral corpus caveosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Host
Rabbit
Immunogen
arginase, type II
Isotype
IgG
Molecular Weight
39 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ARG2, Arginase 2, mitochondrial, arginase, type II, Kidney type arginase, Non hepatic arginase, Type II arginase
Uniprot
P78540
Gene Id
384
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)