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Home / Primary Antibodies / Polyclonal Antibodies

ARG1 antibody

SKU : BHA10810616

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Mfr.No.	FNab10829
Background	Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical?marker?of hepatocellular differentiation in fine needle aspiration cytology and a marker?of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alteative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alteative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).
Clonality	polyclonal
Host	Rabbit
Immunogen	arginase, liver
Immunogen Region	transducin-like enhancer of split 1
Isotype	IgG
Molecular Weight	25-40 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	ARG1, Arginase 1, liver Arginase, Liver type arginase

Uniprot	P05089
Gene Id	383
Research Area	Signal Transduction, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IF: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10855.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810616	FNab10829	100ug	$300		Add to Cart

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