This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals. Alteative splicing results in multiple transcript variants.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Host
Rabbit
Immunogen
adaptor-related protein complex 1, mu 2 subunit
Isotype
IgG
Molecular Weight
48 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
AP 1 complex subunit mu 2, AP mu chain family member mu1B, AP1 mu2, AP1M2, HSMU1B, MU 1B, Mu adaptin 2, MU1B, Mu1B adaptin, mu2
Uniprot
Q9Y6Q5
Gene Id
10053
Research Area
Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)