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Home / Primary Antibodies / Promotion

ALR antibody

SKU : BHA10800345

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Mfr.No.	FNab00349
Alternative Names	ALR ; ERV1 ; GFER ; Hepatopoietin ; HERV1 ; HPO ; HPO1 ; HPO2 ; HSS
Background	The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Mitochondria, Secreted
Clonality	polyclonal
Description	GFER(FAD-linked sulfhydryl oxidase) is also named as ALR, HERV1, HPO. It plays an important role in the disulfide relay system (DRS) in human mitochondria.The GFER gene codes for 2 distinct isoforms that are probably synthesized from the same mRNA with the use of different initiation codons. The long isoform (205 amino acids, 23 kD) is located mainly in the mitochondrial intermembrane space and exists under nonreducing and nondenaturing conditions as a homodimer and a heterodimer. The shorter isoform (125 amino acids, 15 kD), which lacks 80 amino acids at its N terminus compared to the longer isoform, is present predominantly in the nucleus(PMID:19409522).
Host	Rabbit
Immunogen	growth factor, augmenter of liver regeneration
Isotype	IgG
Molecular Weight	23-25 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm, Mitochondrion, Secreted
Synonyms	ALR, ERV1, GFER, Hepatopoietin, HERV1, HPO, HPO1, HPO2, HSS

Uniprot	P55789
Gene Id	2671
Research Area	Developmental biology, Stem Cells, Metabolism
Weight	15kDa和23kDa,observed 23kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:200-1:2000
IP	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00349.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800345	FNab00349	100ug	$300		Add to Cart

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