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Home / Primary Antibodies / Polyclonal Antibodies

AKR1A1 antibody

SKU : BHA10800258

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Mfr.No.	FNab00260
Alternative Names	AKR1A1 ; Alcoholdehydrogenase[NADP+] ; Aldehydereductase ; ALDR1 ; ALR ; ARM ; DD3
Background	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alteatively spliced transcript variants of this gene exist, all encoding the same protein.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Host	Rabbit
Immunogen	aldo-keto reductase family 1, member A1 (aldehyde reductase)
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AKR1A1, Alcohol dehydrogenase (NADP+), Aldehyde reductase, ALDR1, ALR, ARM, DD3

Uniprot	P14550
Gene Id	10327
Research Area	Metabolism
Weight	37kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000
IP	1:200-2000
IF	1:50-500

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab00260.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800258	FNab00260	100ug	$300		Add to Cart

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