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Home / Primary Antibodies / Polyclonal Antibodies

ADAR1 antibody

SKU : BHA10800149

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Mfr.No.	FNab00150
Alternative Names	ADAR ; ADAR1 ; adenosinedeaminase ; RNA ; DRADA ; DSH ; DSRAD ; G1P1 ; IFI4 ; IFI4 ; Interferoninducibleprotein4
Background	ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible 150 kDa protein and a constitutively expressed N-terminally truncated 110 kDa protein, encoded by transcripts with alteative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alteative promoter usage and alteative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).
Categories	Primary Antibodies
Cellular Localization	Nucleus, Ytoplasm
Clonality	polyclonal
Description	ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alteative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alteative promoter usage and alteative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).
Host	Rabbit
Immunogen	adenosine deaminase, RNA-specific
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nucleus,Cytoplasm
Synonyms	ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136

Uniprot	P55265
Gene Id	103
Research Area	Epigenetics, Immunology, Metabolism, Neuroscience
Weight	136kDa,observed 110kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IF, WB, IP

Description

ELISA ; IHC ; IF ; WB ; IP

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IP	1:200-1:2000
IF	1:20-1:200

Tested Application

WB: 1:500-1:2000; IHC: 1:50-1:200; IP: 1:200-1:1000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800149	FNab00150	100ug	$300		Add to Cart

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