TXN2 Antibody

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TXN2 Antibody

Alternative Names Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2), TXN2, TRX2
Antigen TXN2
Categories Primary Antibodies

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suppilerCUSABIO TECHONOLOGY LLC
merchant skuCSB-PA857458ESR2HU
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Description

Description

Alternative Names :
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2), TXN2, TRX2

Antigen :
TXN2

Categories :
Primary Antibodies

Clonality :
polyclonal

Conjugate :
Non-conjugated

Description :
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.

Host :
Rabbit

Immunogen :
Recombinant Human Thioredoxin, mitochondrial protein (1-166AA)

Involvement In Disease :
Combined oxidative phosphorylation deficiency 29 (COXPD29)

Isotype :
IgG

Raised In :
Rabbit

Reactivity :
Human, Mouse, Rat

Regulatory :
RUO

Relevance :
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.

Species :
Homo Sapiens (Human)

Subcellular Location :
Mitochondrion

Target

Target

Uniprot :
Q99757

Database Links :
HGNC:17772
OMIM:609063
KEGG:hsa:25828
STRING:9606.ENSP00000216185
UniGene:Hs.211929

Function :
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity.

Pathway :
NOD-like receptor signaling pathway

Protein Families :
Thioredoxin family

Research Area :
Signal Transduction

Tissue Specificity :
Widely expressed in adult (at protein level) and fetal tissues.

Property

Property

Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form :
Liquid

Format :
Liquid

Purification :
Antigen Affinity Purified

Purity :
Antigen Affinity Purified

Storage :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Storage Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications

Applications

Application

Description

Dilution

Dilution: ELISA, WB, IHC

Dilution: ELISA ; WB ; IHC, WB ; ELISA ; IHC

Dilution:

WB	1:500-5000
IHC	1:20-1:200

Dilution: ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200

Protocols

Protocols

Datasheet :

ELISA Protocol :

Western Blotting(WB) Protocol :

Immunohistochemistry (IHC) Protocol :

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