• Alternative Names :
• Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71), ECE1

• Antigen :
• ECE1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• Non-conjugated

• Description :
• Converts big endothelin-1 to endothelin-1.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Endothelin-converting enzyme 1 protein (471-770AA))

• Involvement In Disease :
• Hirschsprung disease, cardiac defects, and autonomic dysfunction (HCAD)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Converts big endothelin-1 to endothelin-1.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell membrane, Single-pass type II membrane protein

• Uniprot :
• P42892

• Database Links :
• 
  

  HGNC:3146

  OMIM:600423

  KEGG:hsa:1889

  STRING:9606.ENSP00000364028

  UniGene:Hs.195080

• Function :
• Converts big endothelin-1 to endothelin-1.

• Protein Families :
• Peptidase M13 family

• Research Area :
• Signal Transduction

• Tissue Specificity :
• All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A an

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :