• Alternative Names :
• Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (Protein TREB36), ATF1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Cyclic AMP-dependent transcription factor ATF-1 protein (1-210AA)

• Involvement In Disease :
• Angiomatoid fibrous histiocytoma (AFH)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human, Mouse

• Regulatory :
• RUO

• Relevance :
• This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Uniprot :
• P18846

• Gene Id :
• 466

• Database Links :
• 
  

  HGNC:783

  OMIM:123803

  KEGG:hsa:466

  STRING:9606.ENSP00000262053

  UniGene:Hs.648565

• Function :
• This protein binds the cAMP response element (CRE) (consensus

• Protein Families :
• BZIP family, ATF subfamily

• Research Area :
• Epigenetics and Nuclear Signaling

• Weight :
• 15,295 Da

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :