• Alternative Names :
• Anthrax toxin receptor 1 (Tumor endothelial marker 8), ANTXR1, ATR TEM8

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Description :
• Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Anthrax toxin receptor 1 protein (315-564AA)

• Involvement In Disease :
• Hemangioma, capillary infantile (HCI); GAPO syndrome (GAPO)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cell membrane, Single-pass type I membrane protein, Cell projection, lamellipodium membrane, Single-pass type I membrane protein, Cell projection, filopodium membrane, Single-pass type I membrane protein

• Uniprot :
• Q9H6X2

• Gene Id :
• 84168

• Database Links :
• 
  

  HGNC:21014

  OMIM:230740

  KEGG:hsa:84168

  STRING:9606.ENSP00000301945

  UniGene:Hs.165859

• Function :
• Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

• Pathway :
• NOD-like receptor signaling pathway

• Protein Families :
• ATR family

• Research Area :
• Tags & Cell Markers

• Tissue Specificity :
• Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells.

• Weight :
• 63kDa

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity purified

• Purity :
• Antigen Affinity purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :