• Alternative Names :
• Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase), ADAM9, KIAA0021 MCMP MDC9 MLTNG

• Antigen :
• ADAM9

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• Non-conjugated

• Description :
• Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Disintegrin and metalloproteinase domain-containing protein 9 protein (475-685AA)

• Involvement In Disease :
• Cone-rod dystrophy 9 (CORD9)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Secreted

• Uniprot :
• Q13443

• Gene Id :
• 8754

• Database Links :
• 
  

  HGNC:216

  OMIM:602713

  KEGG:hsa:8754

  STRING:9606.ENSP00000419446

  UniGene:Hs.591852

• Function :
• Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins.

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart.

• Weight :
• 90556

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Immunohistochemistry (IHC) Protocol :