• Alternative Names :
• Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP), CAPN1, CANPL1

• Antigen :
• CAPN1

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• Non-conjugated

• Description :
• Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Calpain-1 catalytic subunit protein (20-330AA)

• Involvement In Disease :
• Spastic paraplegia 76, autosomal recessive (SPG76)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Cytoplasm, Cell membrane

• Uniprot :
• P07384

• Database Links :
• 
  

  HGNC:1476

  OMIM:114220

  KEGG:hsa:823

  STRING:9606.ENSP00000279247

  UniGene:Hs.502842

• Function :
• Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

• Pathway :
• Apoptosis Cellular senescence Necroptosis Protein processing in endoplasmic reticulum

• Protein Families :
• Peptidase C2 family

• Research Area :
• Signal Transduction

• Tissue Specificity :
• Ubiquitous.

• Buffer :
• PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• Antigen Affinity Purified

• Purity :
• Antigen Affinity Purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Datasheet :
• 

• ELISA Protocol :

• Western Blotting(WB) Protocol :

• Immunohistochemistry (IHC) Protocol :