• Alternative Names :
• Mitochondrial import inner membrane translocase subunit Tim10 B (Fracture callus protein 1) (FxC1) (Mitochondrial import inner membrane translocase subunit Tim9 B) (TIMM10B) (Tim10b), TIMM10B, FXC1 TIM9B TIMM9B

• Antigen :
• TIMM10B

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• FITC

• Description :
• Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Mitochondrial import inner membrane translocase subunit Tim10 B protein (1-103AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Mitochondrion inner membrane, Peripheral membrane protein

• Uniprot :
• Q9Y5J6

• Database Links :
• 
  

  HGNC:4022

  OMIM:607388

  KEGG:hsa:26515

  STRING:9606.ENSP00000419704

  UniGene:Hs.54943

• Function :
• Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

• Protein Families :
• Small Tim family

• Research Area :
• Others

• Tissue Specificity :
• Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :