• Alternative Names :
• Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.4.19.12) (Deubiquitinating enzyme 3) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3), USP3

• Antigen :
• USP3

• Categories :
• Primary Antibodies

• Clonality :
• polyclonal

• Conjugate :
• Biotin

• Description :
• Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.

• Host :
• Rabbit

• Immunogen :
• Recombinant Human Ubiquitin carboxyl-terminal hydrolase 3 protein (201-500AA)

• Isotype :
• IgG

• Raised In :
• Rabbit

• Reactivity :
• Human

• Regulatory :
• RUO

• Relevance :
• Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.

• Species :
• Homo Sapiens (Human)

• Subcellular Location :
• Nucleus

• Uniprot :
• Q9Y6I4

• Database Links :
• 
  

  HGNC:12626

  OMIM:604728

  KEGG:hsa:9960

  STRING:9606.ENSP00000369681

  UniGene:Hs.458499

• Function :
• Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin.

• Protein Families :
• Peptidase C19 family, USP3 subfamily

• Research Area :
• Epigenetics and Nuclear Signaling

• Tissue Specificity :
• Expressed in all tissues examined, with strongest expression in pancreas.

• Buffer :
• Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Form :
• Liquid

• Format :
• Liquid

• Purification :
• >95%, Protein G purified

• Purity :
• >95%,Protein G purified

• Storage :
• Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

• Storage Buffer :
• 
  
  Preservative: 0.03% Proclin 300
  Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

• Datasheet :
• 

• ELISA Protocol :